People

Maria Paula do Amaral Alegria Guedes de Pinho

Independent Researcher

Research Group
Toxicology
Position
Coordinating Investigator (since 2016)
Personal Website
View here
Email
pguedes@ff.up.pt
Phone number
220428000 (8796)
Researcher ID
D-4847-2013
ORCID
0000-0002-7395-5700
Ciência Vitae
2510-1418-EF48

Recent publications

  • Araujo, AM; Carvalho, M; Costa, VM; Duarte, JA; Dinis-Oliveira, RJ; Bastos, MD; de Pinho, PG; Carvalho, F. 2021. In vivo toxicometabolomics reveals multi-organ and urine metabolic changes in mice upon acute exposure to human-relevant doses of 3,4-methylenedioxypyrovalerone (MDPV). ARCHIVES OF TOXICOLOGY, 95, DOI: 10.1007/s00204-020-02949-2
  • Furtado, I; Oliveira, AS; Amaro, F; Lopes, P; Cabral, M; Bastos, MD; de Pinho, PG; Pinto, J. 2021. Volatile profile of cork as a tool for classification of natural cork stoppers. TALANTA, 223, DOI: 10.1016/j.talanta.2020.121698
  • Moreira, F; Carmo, H; de Pinho, PG; Bastos, MD. 2021. Doping detection in animals: A review of analytical methodologies published from 1990 to 2019. Drug Testing and Analysis, DOI: 10.1002/dta.2999
  • Oliveira, AS; Furtado, I; Bastos, MD; de Pinho, PG; Pinto, J. 2020. The influence of different closures on volatile composition of a white wine. FOOD PACKAGING AND SHELF LIFE, 23, DOI: 10.1016/j.fpsl.2020.100465
  • Silva, B; Silva, R; Fernandes, C; de Pinho, PG; Remiao, F. 2020. Enantioselectivity on the absorption of methylone and pentedrone using Caco-2 cell line: Development and validation of an UHPLC method for cathinones quantification. TOXICOLOGY AND APPLIED PHARMACOLOGY, 395, DOI: 10.1016/j.taap.2020.114970

Main research interests

  • 1. Development of GC-MS methodologies to determine low molecular weight compounds in different biological matrices: in vitro and ex vivo cellular systems, plasma and urine.
  • 2. Studies of “legal” drugs of abuse toxicity by using in vitro and in vivo models.
  • 3. Use of Metabolomics to prostate, bladder and renal cell carcinoma Detection and Biomarker Discovery.
  • 4. Use metabolomic to dissect mechanisms of action and to find new and sensitive biomarkers of toxicity (Toxicometabolomics).

Degrees

  • PhD in Biological and Medical Sciences, University of Bordeaux, France (1994)
  • "Agregação" in Toxicology, Universidade do Porto (2019)